Efficacy and safety

AFRAN® can be useful in mild to moderate changes in mood with or without psychosomatic signs and from psycho-functional disturbances, irritability, states of sadness or euphoria, melancholy, grief, cyclical mood changes, anxiety, restlessness, considerable stress from an overload of work or mental fatigue, memory loss and lack of concentration.

Predisposing factors or triggers: Emotional upsets (divorce, sentimental breakups, recent bereavement) Poor self-esteem and body image symptoms (inappropriate self-belief about body shape) Moving to a new home or changes in the social environment, job loss and financial woes, sleep disturbances, hypochondriac attitudes.

Composition

Method of Use

Instructions for use:

Clinical Studies

Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial.

Crocus sativus L. in the Treatment of Mild to Moderate Depression: A Double-blind, Randomized and Placebo-controlled Trial.

Comparison of petal of Crocus sativus L. and fluoxetine in the treatment of depressed outpatients: A pilot double-blind randomized trial.

Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial.